Enemies

Kijuju residents implanted with Type 2 Plagas. They keep their intelligence: they talk, use tools and attack in groups. The rear grab does no damage, but leaves you defenceless while the others hit you: have your partner free you.

• Leg, then rear finisher: Chris does a Neck Breaker, Sheva a Throat Slit. Instant kill, and no Plaga can emerge.
• Head: Chris Straight, Sheva Roundhouse. Leg from the front: Uppercut / Somersault. Arm from the front: Hook / Twist Kick; if you both pincer him, a tag-team finisher follows (Haymaker / Skull Crusher). On the ground: Stomp / Impale.
• Crowds: shotgun and the environment. Awards: Ride the Lightning (transformer), Stop, Drop, & Roll (3 Majini with oil canisters), Baptism by Fire (3 with a drum or gas tank) and Meat Shower (3 with one grenade or Proximity Bomb).
• Weapons: axe, kukri, megaphone, club or wrench (strike, heavy charge and throw); pick or shovel (charge with knockback); crossbow (deflect a bolt with the Knife: Be the Knife); Molotov (shoot one mid-air: Fireworks); dynamite (heavy throw and a kamikaze charge with the fuse lit).

The megaphone Majini who whips up the crowd; he hits you with it too. Kill him like any Town Majini: leg shot and rear finisher.

Shoot the Messenger (DLC): kill the 3 Agitator Majini in Desperate Escape in one run, all by the same player (megaphone Big Man Majini don't count). Easiest on Amateur. - Dock: after the first partner jump, if you cleared every wave in Transport Area 1 before using the Transport Area Key. The hardest one, and it may take several tries; if you are slow he escapes behind the fence. He turns into a Cephalo: leg and finisher. - Turret slope: keep killing the Majini that come out on the high southern walkway before opening the door for Josh. Kill him with the turret or a rifle. - Helipad: he comes up the elevator with 2 Big Man Majini with 26–30 s left, if you killed every boss in time. He turns into a Cephalo: keep a Flash Grenade.

Built like a wrestler, tougher than a normal Majini, and he always gets back up. Unarmed in the campaign. His punches send you flying: make him your first target.

• Shotgun: one semi-upgraded shell → he blocks with crossed arms → Chris Uppercut / Sheva Somersault, and your partner carries the combo on.
• Leg (or Stun Rod, or Hand Grenade) → he kneels → Straight / Roundhouse; hit him again while kneeling → he blocks → another hit → 3-hit finisher (Chris Backhand / Sheva Spinning Back Kick).
• Fast: one S&W M500 head shot kills him, or freeze him with Nitrogen Rounds and shatter him. A Flash Grenade also works.
• The Works: chaining combos on him is the easy route to the award.

Bikers attacking in groups with Molotovs and tomahawks. Red-shirted riders are leaders with more health.

• 2-1: a cutscene with 3 QTEs on random buttons (Sheva shoots the chain round Chris's ankle).
• 2-3: from the Gambit's Mounted Machine Guns, shoot riders or bikes. Shoot the thrower's arm before he throws and he drops the Molotov on himself. Flatbed trucks try to ram the Gambit and carry Molotov throwers: focus fire until they explode and watch both sides.
• Drive By: stop an armoured truck by taking out the driver. The 2-1 bridge truck can be stopped by shooting the driver, the truck or an explosive barrel (the easiest, recommended on Professional).

Ndipaya warriors with Type 3 Plagas: war paint, ancestral weapons, great endurance and an incredible jump. Ladders won't save you: they leap up.

• Archers first: snipe the longbow users (a slow explosive arrow with very long range that also hits other Majini) and the bomb throwers (they explode on ground or water, with a wider radius than arrows).
• Torch: fire breath (a long stun) and the rampage (a crouching run, then spinning torches), probably the most damaging Majini attack. Kill him before he closes in.
• Spear: the impale (running start, lifts and slams you) hits hard; the leaping stab has a dodge prompt, and walking forward also avoids it.
• Shield: shotgun up close or leg shots.
• Up close, shotgun. If one holds you from behind while the others attack, have your partner free you.

Former soldiers and mercenaries guarding the Tricell base, far better trained than other Majini: handguns, AK-74s, grenades, Stun Rods, rocket launchers, armour, helmets and bulletproof shields.

• Rocket launchers: one rocket puts you in DYING on any difficulty. Only in 5-2, 6-1 and 6-3. They reload slowly: that's your window. Kill them first, along with the Stun Rod carriers.
• AK-74: bursts that knock you down if several hits land in a row. Take cover and shoot while they reload. Up close they club you with the butt. After downing you they fire into the air to taunt: take the opening.
• Stun Rod: the backhand always stuns; the running swing knocks you back.
• Shield: a shove, often followed by a Stun Rod swing.
• Grenades: thrown behind your cover to flush you out.
• Gas-mask wearers are immune to Flash Grenade blinding.
• Some swell up and explode before dying (small radius, catastrophic up close).

The Plaga bursts from the Majini's neck after enough damage; it's the same species as the Ganado Plaga from RE4 and, like it, weak to light. Its body stretches a long way: back off.

• Prevent it: knee shot and rear finisher on suspected carriers (use it a lot in the 2-2 Mines). The Stun Rod, the Rocket Launcher and Nitrogen Rounds also stop it.
• Once it's out: shotgun to knock it back, then shoot the Plaga. It can still be downed and meleed, but that is no longer an instant kill.
• Go into the Light: kill 2 enemies with one Flash Grenade.

Large dogs with a Plaga; their heads split in two. They come in packs of 2 or more.

• Incendiary Grenade: very effective against the pack.
• Shotgun in narrow corridors: one blast hits and knocks down several.
• They can't climb: get on high ground (in 2-2, onto the railcars). In 2-2 you can also wait by the tripwire explosives and shoot them as the dogs arrive.
• With the head split they grapple you; some grow tentacles from it.

A Plaga that ejects from a badly damaged Majini and flies on four wing-like limbs. It's clumsy, but its tail brought down the Alpha Team's helicopter. It sidesteps when you aim at it (strafes on higher difficulties).

• Shotgun: the best option.
• Prevent it: rear finisher on the carrier. A carrier killed indoors only loses its head: no Kipepeo comes out.
• If it wraps its tail round your neck it strangles you, and if you are already badly hurt, it snaps your neck.

A Plaga bursting from the upper half of a Majini, leaving the torso hanging below. Hard exoskeleton; up close it opens into a mouth that swallows its victim.

• Its bite puts you in DYING, and a second bite before you are revived kills you. Its headbutt (320) is slow and easy to read.
• Prevent it: a Majini covered in bubbles is turning into a Duvalia: rear-finish it or freeze it with Nitrogen Rounds. A Majini killed on the ground can't transform.
• Once it's out: shotgun the feet so it kneels and opens up, then magnum the core. Or climb a ladder: with no arms it can't follow.
• Don't mix them up: a Base Majini that inflates like a balloon, clutches its head and smokes from the back is about to explode; one more shot sets it off at once.

A Plaga that leaves its host to hunt alone, spider-like; they come in packs and many burrow out of the ground. They have one attack: leaping on you and wrapping their legs round you to drain health. The damage is low (lower with the Melee Vest), but you can't defend yourself and you move slowly, and there is no button to break free: wait, or have your partner knife it off.

• Strafe and the leap misses.
• A single one dies very easily.
• Go into the Light: kill 2 enemies with one Flash Grenade; Bui Kichwa are the easy target.

It lunges once when you break its hiding place (tiny damage) and is harmless after that. Kill it with the Knife to save bullets. Killing a Majini with a thrown Egg (Rotten) earns Egg on Your Face.

15–20 ft crocodiles in waist-deep water. Their bite is instant death, they respawn and give nothing: avoid them. AI Sheva and the crocodiles ignore each other. On the 3-2 raft follow the QTE: that one can't be killed.

A Progenitor Virus refinement of the Licker: nearly blind, hunting by hearing and smell, and clinging to walls and ceilings. Its pounce pins you and tears your throat: instant death, with a single counter prompt; miss it and your partner has to save you.

• Stealth: walk, holster your weapon and don't kick doors open: they won't notice you.
• One or two: handgun to the brain → it coils back and shows the weak spot → shoot it → it falls and sometimes stays down → Stab.
• Hordes: grenades, shotgun, magnum or Acid Rounds. Shoot them while they are still on the walls. In 5-3, Proximity Bombs while you push the container.

Small flying bugs that come out of the U-8's abdomen. They die easily. Don't ignore them when you are short on ammo: wait for a swarm to gather and clear it with the shotgun.

Emaciated failed Uroboros test subjects lying on the belt. They only lunge when you are close: follow the dodge prompts and save your ammo (IGN). Kill the area's Reaper first so you don't face both at once.

In Lost in Nightmares, knife them to stun them or sidestep past; if one grabs you, your partner helps or you rotate the stick.