Super Tyrant

Chapter: 12 · Side Street and Blackthorn Station
Where: The Side Street beside the Basketball Court, past Gun Shop Kendo, full of wrecked cars.

Weak point

The exposed heart in its chest, its only weak point.

The T-501 grabs an RPG missile, Leon blows it up and that destroys its power limiter: it becomes the Super Tyrant, with a claw arm and its heart exposed. The fight is mandatory. Use the Requiem without hesitating (the place for the rounds you've saved), then the rifle or shotgun; handguns are a bad trade. Enough heart damage drops it to one knee: 2-3 hatchet strikes to the heart kill it.

Before you start: save at the Side Street Supply Box, upgrade the Hatchet's durability and buy or repair your Body Armor.

Reward

Credits (wiki) and the I Remember That, Too trophy (200 CP).

No published HP. Med Injectors and ammo are scattered around the arena (PCGamesN). One guide says its swing has an audio cue just before impact, so you can parry by ear (unconfirmed). It returns as a stage boss in Leon Must Die Forever (see Extras).

Step by step

Dragging-claw charge: parry (L) or step aside. It slides past you: shoot its chest as it turns around.
Parryable: the charge, the mid-range lunging stab, the wide punches and the 3-hit combo (the parry doesn't stun it: retaliate after the third swipe). With an unupgraded Hatchet one parry can use up the edge; Game8 counts about 2 parries per sharpening.
Not parryable: the leap slam from a car roof and thrown cars. Near a car it can swat it into you: don't stand between it and a car. If it lifts one, move back and left, then sprint across the arena.
Mid-range: too far and it throws cars; too close and it grabs you.
Car-top phase: it jumps onto a car and pauses. That's free heart damage; enough of it knocks it off and stuns it. If you fall short, get ready to dodge the leap. Use quiet moments to sharpen (L + Y).
Stunned → hatchet: when it drops to one knee, run in and use the prompt to hack at the heart (heavy damage). It takes 2 or 3 (IGN: at least two stuns; the second prompt usually ends it). If you're far away, use the stun to heal (R) or reload instead.