Uriaș (the Stronghold)

Chapter: 10 · The Stronghold · Otto's Mill
Where: The Large Cavern (Stronghold B1): a U-shaped cavern with stone pillars and a raised central plateau.

Weak point

Game8 says "none"; the game data gives head ×2.6 (Knife ×1.73) and the rest ×2.0. Explosives ×2.0. GM 79 grenades and Flashbangs stun him.

The ambush Uriaș comes back as a required boss. Save first in the Small Cavern: typewriter, First Aid Med, Explosive Rounds ×2 and Sniper Rifle Ammo ×5.

Supplies in the cavern alcoves (grab them while he is still on the plateau): First Aid Med (W), Handgun Ammo ×30 + 2 Pipe Bombs (NE), Shotgun Ammo ×4 + Sniper Rifle Ammo ×4 (SE).

Moves: a jumping hammer slam (he crouches first: run in a straight line); hammer swings and a spin; a chasing charge that ends in a slam; he tears out pillars and throws them (hide behind another or run to the far side of the U); and he climbs back to the plateau to roar for 1-2 Lycans.

Reward

Crystal Hammer (35,000 Lei) and the Up Urs! challenge.

25,000 HP. Rough estimate at Standard's starting rank: about 6 un-upgraded M1851 Wolfsbane shots to the head, or about 17 Mines. Game8's weapons: W870 TAC, M1911, GM 79, M1851 Wolfsbane, Mines and Pipe Bombs.

Village of Shadows: PowerPyx says this is where the grenade launcher starts falling short; bring an infinite S.T.A.K.E. (New Game+). Game8 recommends the magnum, and blocking when you can't dodge.
Knives Out: circle him and sidestep the leap.

Step by step

Before he jumps down, lay Mines and open with rifle or magnum shots to the face.
When he crouches, run in a straight line away from the leap. When he lands, M1851 Wolfsbane or GM 79 to the face.
Keep your distance (one hit puts you in the red) and use the pillars against his swings.
If he tears out a pillar, hide behind another or go to the other end of the U.
When he climbs up to roar, kill the Lycans fast: a GM 79 grenade or a Pipe Bomb hits them and him at once.
After enough damage he kneels for a moment (rarely): unload everything.