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RE4 Guide

Bosses — quick reference

the full strategy lives in each chapter

Dr. Salvador

1-1 / 1-3

Shotgun to the head → ground → knife. Or the tripwire trick. One chainsaw hit = death.

Ruby 10,000pts

Del Lago

1-3

Infinite harpoons; dodge the weed piles by veering right. Final rope-cutting QTE.

Required for the lake key

El Gigante

2-1 · 2-3 · 4-2 ×2

TMP to the head → it kneels → climb on and knife the parasite. The dog helps in 2-1; in 4-2, one falls into the lava via the lever.

15,000pts each

Bitores Mendez

2-3

Phase 1: 3 incendiary grenades at his feet. Phase 2: Red9/TMP while he moves along the beams, shotgun or Frag when he closes in.

30,000pts + fake eye

Garrador ×4

3-1 → castle

Blind. Walk, don't run. The back parasite is its weak point — rifle or shotgun from behind. In the cage: Frag the door and get out.

15,000pts each

Verdugo

4-1

Nearly immune to bullets. Knock down an N2 tank when it's close (freezes it: ×3 damage) and land a rocket. Avoidable, but you lose the jewel.

Crown Jewel

Ramón Salazar

4-4

Shoot the central tentacle's eye → the "flower" opens and exposes Salazar → rocket or sustained magnum. Buy the rocket beforehand.

50,000pts

J.J. (Gatling Man)

5-1 / 5-4 ×2

The heaviest-armed of Saddler's militia, wielding a personal Gatling gun. He only fires with a direct line of sight, and there's a spin-up pause before the burst — take cover, use a Flash grenade to stun him, then unload your strongest weapon (rifle/magnum to the head).

15,000pts each (3 total)

Regenerator / Iron Maiden

5-1 →

Thermal scope on the rifle → shoot the hidden parasites. Iron Maidens carry an extra one on their back; they explode on death.

5,000–20,000pts

U-3 "It"

5-3

In the containers it can't die: shoot the green buttons and dodge. In its lair use red barrels + the door trap.

50,000pts

Jack Krauser

5-3

Knife QTE first. In the tower (3 min): legs only → magnum to the head. The knife alone deals huge damage to him.

Snake piece

Osmund Saddler

Final

Shoot the leg eyes → the central eye is exposed → knife/magnum. Cranes and red barrels = free damage. Finisher: Ada's rocket launcher.

100,000pts

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